Our 2SPR pushes the limits of detection and sensitivity in label-free interaction analysis.
The 2SPR Dual Channel System is the next generation of surface plasmon resonance (SPR) technology with incomparable sensitivity and high-quality binding data for interaction analysis - all in a flexible component-based platform. The key to the system is the advanced 2SPR Dual Channel SPR Spectrometer instrument.
The 2SPR label-free system generates data on critical interactions between proteins, nucleic acids, lipids, carbohydrates, small molecules, whole cells, bacteria, viruses, and polymers.
The 2SPR System is used in pharmaceuticals, drug discovery, antibody screening, protein structure and function, gene regulation, and systems biology.
Exceptional sensitivity in the 2SPR System provides real-time data and is ideal for:
- High quality kinetic analysis
- Affinity measurements ranging from 1mM to 1pM
- Precise determination of thermodynamic parameters
- Accurate concentration analysis
Advantages of the modular component-based design
- Ultimate flexibility for cost-effective biomolecular interaction analysis
- Minimal maintenance requirements with off-the-shelf fluidics
- Low life cycle costs
- All components are purchased separately or as a system providing for easy upgrades.
- User-maintainable with minimal maintenance required, eliminating the need for yearly service contracts.
| Technical Specifications: 2SPR | Measurement channels | 2 | Sample loading | Autosampler or SAV | Temperature range | 10-70°C | Degassing unit | Optional degassing unit | Flow rate range | 1-1000 µL/min with SR8500 pump | 21 CFR Part 11 compliance | yes | Sample volume | With SAV 1-5000 µL with Autosampler 1-1000 µL | Refractive index Resolution | < 10⁻⁸ RU | Refractive index range | 1.33 – 1.40 (@780 nm) | Analyte concentration range | 1 mM – 1 pM | Minimum molecular weight detection | < 100 Da | Baseline noise | 0.05 RU RMS @25 µL/min | Baseline drift | < 0.01 RU/min | Association rate constant | 10³ – 10⁷ M⁻¹s⁻¹ | Dissociation rate constant | 10⁻¹ – 10⁻⁶ s⁻¹ | Equilibrium dissociation constant | mM – 1 pM | Available flow cells | µ-flow cell, UV-, electrochemical flow cell etc. |
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