Products | SPR Biosensors | SPR Systems | System Comparison

Comparison of
SPR systems

4SPR2SPRSR7000DC
Number of flow channels422
Fully automated / semi automated configuration/–//
Information provided
Kinetic and affinity data (KD, ka, and kd)
Specificity
Selectivity
Concentration
Thermodynamic data (ΔH)
Refractive index
Data presentation
Real-time monitoring of sensorgrams
Online reference subtraction
Result tables
Result plots
Instrument operations
Buffer degassing (* requires degassing unit)**
Buffer selection valve
Temperature range of flow cell (°C)10 – 7010 – 7010 – 70
Injection volume (µl) fully automated systems1 – 40001 – 40001 – 4000
Required sample volume injection volume +15-30 µLinjection volume +15-30 µLinjection volume +15-30 µL
Injection volume (µl) semi automated systems (requires Semiautomatic Valve)1 – unlimited1 – unlimited
Sample storage temperature (only with autosampler)4°C or ambient4°C or ambient4°C or ambient
Unattended operation (only with autosampler)> 48h> 48h> 48h
Detection limit (MW)No lower limit for organic molecules< 100 Da≥ 200 Da
Sample types
Biological sample types
LMW drug candidates (incl. DMSO-containing buffers)+++++++
Proteins, peptides (also DNA, RNA polysaccharides, lipids), in various sample environments (e. g. plasma and serum)+++++++++
Cells and viruses in various sample environments (e. g. plasma and serum)++++++++
Non-biological samples
Pure solvents (DMF, EtOH, DMSO etc.)++++++
Concentrated acids, or bases ++++++
Viscous solutions and suspensions e.g. of polymers, nano particles, colloids+++++++
Compatible Flow cells
4-channel flow cell (60 nL flow channel volume)
2 channel µ-flow cell (80 nL flow channel volume)**
2 channel standard flow cell (140 nL flow channel volume)
2-channel static cuvette**
2-channel microscope flow cell**
2 channel quartz window flow cell**
2 channel electrochemisty flow cell**
2-channel high temperature flow cell
Compatible system components
Diverter valve (required for 2 channel µ-flow cell)integrated
Semi automatic injection valve
Degassing unitintegrated
Software controlled pumpintegrated
21 CFR Part 11 compliance
Remote maintenance / instrument diagnostics
Preventive maintenance by user

**in 2-channel detection mode

4SPR
4SPR
2SPR
2SPR
SR7000DC
SR7000DC