QZ sensor chips (SiO2-coated)
XanTec’s QZ sensor chips are coated with an approximately 10 nm silicon dioxide (SiO2) layer deposited on a 44 nm gold film. These chips are intended for lipid bilayer immobilization, custom surface development on oxidic substrates, or use as a reference surface.
Direct adsorption-based ligand immobilization is not recommended, as it typically results in low immobilization capacity, partial denaturation of protein ligands, and elevated nonspecific background signals, limiting suitability for standard SPR interaction analyses.
Please note that the deposited SiO2 layer induces a substantial SPR signal offset of approximately 20,000 µRIU, which should be considered during experimental setup and data interpretation.
Key features:
- Base sensor chip: Provides a dense, well-defined SiO2 surface suitable for development and evaluation of custom surface chemistries on oxidic materials.
- Reference chip: Serves as a control surface for assessing nonspecific interactions or benchmarking newly developed sensor coatings.
| Product code | QZ |
|---|---|
| Base coating | SiO2, ≈ 10 nm, on gold support |
| Intended purpose |
|
1 All illustrations are schematic representations and are not drawn to scale; dimensions, densities, and spatial relationships do not reflect actual physical or chemical proportions.