XanTec bioanalytics has developed a selection of hydrogel coated slides for both DNA and protein microarrays. DNA microarrays require low background signal, and minimal intra- and slide-to-slide deviation is crucial. Spotting is usually a straightforward process, as DNA is relatively robust. On the other hand, protein microarrays are more delicate. Proteins can't be immobilized on the same types of materials, for they are extremely sensitive to the physical and chemical properties of any particular substrate. In addition, protein interaction surfaces must be bioinert and have to provide a much higher immobilization capacity than that required in DNA microarrays. Therefore, our microarray slide portfolio is specialized and divided into DNA and protein sections.
Information on our high capacity HC hydrogel coatings can be found here:
Short brochure HC Hydrogel Slides
For technical details, please check our technical notes on substrates for protein and for DNA microarrays:
CX DNA Microarray Slides
HCX Slides for Protein Microarrays
The HC hydrogel coatings for protein microarray spotting have been used successfully in highly selective cell separation and immobilization. You can find more information on this award-winning application here: